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Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution

Changes in chromosome number impair fitness by disrupting the balance of gene expression. Here we analyze mechanisms to compensate for changes in gene dose that accompanied the evolution of sex chromosomes from autosomes. Using single-copy transgenes integrated throughout the Caenorhabditis elegans...

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Pubblicato in:eLife
Autori principali: Wheeler, Bayly S, Anderson, Erika, Frøkjær-Jensen, Christian, Bian, Qian, Jorgensen, Erik, Meyer, Barbara J
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047749/
https://ncbi.nlm.nih.gov/pubmed/27572259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17365
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