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Chromosome-wide mechanisms to decouple gene expression from gene dose during sex-chromosome evolution

Changes in chromosome number impair fitness by disrupting the balance of gene expression. Here we analyze mechanisms to compensate for changes in gene dose that accompanied the evolution of sex chromosomes from autosomes. Using single-copy transgenes integrated throughout the Caenorhabditis elegans...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Wheeler, Bayly S, Anderson, Erika, Frøkjær-Jensen, Christian, Bian, Qian, Jorgensen, Erik, Meyer, Barbara J
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047749/
https://ncbi.nlm.nih.gov/pubmed/27572259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17365
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