Epb41l5 competes with Delta as a substrate for Mib1 to coordinate specification and differentiation of neurons

We identified Erythrocyte membrane protein band 4.1-like 5 (Epb41l5) as a substrate for the E3 ubiquitin ligase Mind bomb 1 (Mib1), which is essential for activation of Notch signaling. Although loss of Epb41l5 does not significantly alter the pattern of neural progenitor cells (NPCs) specified as n...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Matsuda, Miho, Rand, Kinneret, Palardy, Greg, Shimizu, Nobuyuki, Ikeda, Hiromi, Dalle Nogare, Damian, Itoh, Motoyuki, Chitnis, Ajay B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047669/
https://ncbi.nlm.nih.gov/pubmed/27510968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138743
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