GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes

Toll-like receptors (TLR) are crucial sensors of microbial agents such as bacterial or viral compounds. These receptors constitute key players in the induction of inflammation, e.g. in septic or chronic inflammatory diseases. Colony-stimulating factors (CSFs) such as granulocyte-macrophage-CSF (GM-C...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Sadeghi, Kambis, Wisgrill, Lukas, Wessely, Isabelle, Diesner, Susanne C., Schüller, Simone, Dürr, Celia, Heinle, Armando, Sachet, Monika, Pollak, Arnold, Förster-Waldl, Elisabeth, Spittler, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047522/
https://ncbi.nlm.nih.gov/pubmed/27695085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162667
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