GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes

Toll-like receptors (TLR) are crucial sensors of microbial agents such as bacterial or viral compounds. These receptors constitute key players in the induction of inflammation, e.g. in septic or chronic inflammatory diseases. Colony-stimulating factors (CSFs) such as granulocyte-macrophage-CSF (GM-C...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Sadeghi, Kambis, Wisgrill, Lukas, Wessely, Isabelle, Diesner, Susanne C., Schüller, Simone, Dürr, Celia, Heinle, Armando, Sachet, Monika, Pollak, Arnold, Förster-Waldl, Elisabeth, Spittler, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047522/
https://ncbi.nlm.nih.gov/pubmed/27695085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162667
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