Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia

OBJECTIVE: To investigate serum neurofilament light chain (NfL) concentrations in frontotemporal dementia (FTD) and to see whether they are associated with the severity of disease. METHODS: Serum samples were collected from 74 participants (34 with behavioral variant FTD [bvFTD], 3 with FTD and moto...

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Udgivet i:Neurology
Main Authors: Rohrer, Jonathan D., Woollacott, Ione O.C., Dick, Katrina M., Brotherhood, Emilie, Gordon, Elizabeth, Fellows, Alexander, Toombs, Jamie, Druyeh, Ronald, Cardoso, M. Jorge, Ourselin, Sebastien, Nicholas, Jennifer M., Norgren, Niklas, Mead, Simon, Andreasson, Ulf, Blennow, Kaj, Schott, Jonathan M., Fox, Nick C., Warren, Jason D., Zetterberg, Henrik
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047041/
https://ncbi.nlm.nih.gov/pubmed/27581216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003154
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