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Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis

Thiazolinyl imine reductases catalyze the NADPH-dependent reduction of a thiazoline to a thiazolidine, a required step in the formation of the siderophores yersiniabactin (Yersinia spp.) and pyochelin (Pseudomonas aeruginosa). These stand-alone nonribosomal peptide tailoring domains are structural h...

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Publicat a:Biochemistry
Autors principals: Meneely, Kathleen M., Ronnebaum, Trey A., Riley, Andrew P., Prisinzano, Thomas E., Lamb, Audrey L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046821/
https://ncbi.nlm.nih.gov/pubmed/27601130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00735
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