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Resistance to Macrolide Antibiotics in Public Health Pathogens
Macrolide resistance mechanisms can be target-based with a change in a 23S ribosomal RNA (rRNA) residue or a mutation in ribosomal protein L4 or L22 affecting the ribosome’s interaction with the antibiotic. Alternatively, mono- or dimethylation of A2058 in domain V of the 23S rRNA by an acquired rRN...
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| 發表在: | Cold Spring Harb Perspect Med |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5046686/ https://ncbi.nlm.nih.gov/pubmed/27527699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a025395 |
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