A population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patients

The role of pharmacokinetic-guided dosing of factor concentrates in hemophilia is currently a subject of debate and focuses on long-term prophylactic treatment. Few data are available on its impact in the perioperative period. In this study, a population pharmacokinetic model for currently registere...

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Publicat a:Haematologica
Autors principals: Hazendonk, Hendrika, Fijnvandraat, Karin, Lock, Janske, Driessens, Mariëtte, van der Meer, Felix, Meijer, Karina, Kruip, Marieke, Gorkom, Britta Laros-van, Peters, Marjolein, de Wildt, Saskia, Leebeek, Frank, Cnossen, Marjon, Mathôt, Ron
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046645/
https://ncbi.nlm.nih.gov/pubmed/27390359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.136275
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