Intestinal bacteria are necessary for doxorubicin-induced intestinal damage but not for doxorubicin-induced apoptosis

Doxorubicin (DOXO) induces significant, but transient, increases in apoptosis in the stem cell zone of the jejunum, followed by mucosal damage involving a decrease in crypt proliferation, crypt number, and villus height. The gastrointestinal tract is home to a vast population of commensal bacteria a...

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Detaylı Bibliyografya
Yayımlandı:Gut Microbes
Asıl Yazarlar: Rigby, Rachael J., Carr, Jacquelyn, Orgel, Kelly, King, Stephanie L., Lund, P. Kay, Dekaney, Christopher M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Research Paper/Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046166/
https://ncbi.nlm.nih.gov/pubmed/27459363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2016.1215806
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