Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice

Sepsis-induced lymphopenia is a major cause of morbidities in intensive care units and in populations with chronic conditions such as renal failure, diabetes, HIV and alcohol abuse. Currently, other than supportive care and antibiotics, there are no treatments for this condition. We developed an in...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Doerflinger, Marcel, Glab, Jason, Nedeva, Christina, Jose, Irvin, Lin, Ann, O’Reilly, Lorraine, Allison, Cody, Pellegrini, Marc, Hotchkiss, Richard S., Puthalakath, Hamsa
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046154/
https://ncbi.nlm.nih.gov/pubmed/27694827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34702
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