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Systemic Inhibition of CREB is Well-tolerated in vivo

cAMP-response element binding protein (CREB) is a nuclear transcription factor activated by multiple extracellular signals including growth factors and hormones. These extracellular cues activate CREB through phosphorylation at Ser133 by various protein serine/threonine kinases. Once phosphorylated,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Bingbing X., Gardner, Ryan, Xue, Changhui, Qian, David Z., Xie, Fuchun, Thomas, George, Kazmierczak, Steven C., Habecker, Beth A., Xiao, Xiangshu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046085/
https://ncbi.nlm.nih.gov/pubmed/27694829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34513
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