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Probing unnatural amino acid integration into enhanced green fluorescent protein by genetic code expansion with a high-throughput screening platform

BACKGROUND: Genetic code expansion has developed into an elegant tool to incorporate unnatural amino acids (uAA) at predefined sites in the protein backbone in response to an amber codon. However, recombinant production and yield of uAA comprising proteins are challenged due to the additional transl...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Wandrey, Georg, Wurzel, Joel, Hoffmann, Kyra, Ladner, Tobias, Büchs, Jochen, Meinel, Lorenz, Lühmann, Tessa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045631/
https://ncbi.nlm.nih.gov/pubmed/27733867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-016-0031-6
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