17β-Estradiol up-regulates UDP-glucuronosyltransferase 1A9 expression via estrogen receptor α

UDP-glucuronosyltransferase 1A9 (UGT1A9) is a major phase II enzyme responsible for elimination of drugs and endogenous molecules. Clinical data have shown increased elimination of UGT1A9 substrates in pregnant women or oral contraceptive users, but the role of estrogen in the regulation of UGT1A9 e...

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Bibliografische gegevens
Gepubliceerd in:Acta Pharm Sin B
Hoofdauteurs: Cho, Sung-joon, Ning, Miaoran, Zhang, Yanyan, Rubin, Leah H., Jeong, Hyunyoung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045538/
https://ncbi.nlm.nih.gov/pubmed/27709019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.04.005
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