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The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma

Receptor tyrosine kinases-based autocrine loops largely contribute to activate the MAPK and PI3K/AKT pathways in melanoma. However, the molecular mechanisms involved in generating these autocrine loops are still largely unknown. In the present study, we examine the role of the transcription factor R...

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Publicado en:Oncotarget
Autores principales: Boregowda, Rajeev K., Medina, Daniel J., Markert, Elke, Bryan, Michael A., Chen, Wenjin, Chen, Suzie, Rabkin, Anna, Vido, Michael J., Gunderson, Samuel I., Chekmareva, Marina, Foran, David J., Lasfar, Ahmed, Goydos, James S., Cohen-Solal, Karine A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045426/
https://ncbi.nlm.nih.gov/pubmed/27102439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8822
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