Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells

RNA Polymerase II Elongation Factor (ELL)-associated factor 2 (EAF2) is a tumor suppressor frequently down-regulated in human prostate cancer. We previously reported that its binding partner ELL1 can enhance EAF2 protein stability and activity. Here we show that EAF2 can be polyubiquitinated and its...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Yu, Xinpei, Ai, Junkui, Cai, Liquan, Jing, Yifeng, Wang, Dan, Dong, Jun, Pascal, Laura E., Zhang, Jian, Luo, Rongcheng, Wang, Zhou
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045393/
https://ncbi.nlm.nih.gov/pubmed/27058417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8588
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы