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Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells

RNA Polymerase II Elongation Factor (ELL)-associated factor 2 (EAF2) is a tumor suppressor frequently down-regulated in human prostate cancer. We previously reported that its binding partner ELL1 can enhance EAF2 protein stability and activity. Here we show that EAF2 can be polyubiquitinated and its...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Yu, Xinpei, Ai, Junkui, Cai, Liquan, Jing, Yifeng, Wang, Dan, Dong, Jun, Pascal, Laura E., Zhang, Jian, Luo, Rongcheng, Wang, Zhou
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045393/
https://ncbi.nlm.nih.gov/pubmed/27058417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8588
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