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LOX is a novel mitotic spindle-associated protein essential for mitosis

LOX regulates cancer progression in a variety of human malignancies. It is overexpressed in aggressive cancers and higher expression of LOX is associated with higher cancer mortality. Here, we report a new function of LOX in mitosis. We show that LOX co-localizes to mitotic spindles from metaphase t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boufraqech, Myriem, Wei, Darmood, Weyemi, Urbain, Zhang, Lisa, Quezado, Martha, Kalab, Petr, Kebebew, Electron
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045375/
https://ncbi.nlm.nih.gov/pubmed/27296552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8628
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