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Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Survival for lung cancer patients remains dismal and is largely attributed to treatment resistance. To identify novel target genes the modulation of which could modify platinum resistance, we performed a high-throughput RNAi screen and identified Yes-associated protein (YAP1), a transcription coacti...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Cheng, Haiying, Zhang, Zhenfeng, Rodriguez-Barrueco, Ruth, Borczuk, Alain, Liu, Huijie, Yu, Jiyang, Silva, Jose M., Cheng, Simon K., Perez-Soler, Roman, Halmos, Balazs
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045371/
https://ncbi.nlm.nih.gov/pubmed/26716514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6721
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