Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group

Juvenile myelomonocytic leukemia (JMML) is a rare aggressive disease of early childhood. Driver mutations in the Ras signaling pathways are a key feature of JMML patients. Mutations in SETBP1 and JAK3 were recently identified in a subset of JMML patients characterized by poor prognosis and progressi...

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Publicado en:Oncotarget
Autores principales: Bresolin, Silvia, De Filippi, Paola, Vendemini, Francesca, D'Alia, Mirko, Zecca, Marco, Meyer, Lueder H., Danesino, Cesare, Locatelli, Franco, Masetti, Riccardo, Basso, Giuseppe, te Kronnie, Geertruy
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045366/
https://ncbi.nlm.nih.gov/pubmed/26980750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8016
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