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Mechanisms of neuronal homeostasis: autophagy in the axon
Autophagy is an evolutionarily conserved lysosomal degradation pathway that removes damaged organelles and protein aggregates from the cytoplasm. Being post-mitotic, neurons are particularly vulnerable to the accumulation of proteotoxins and are thus heavily dependent on autophagy to maintain homeos...
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| Published in: | Brain Res |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045311/ https://ncbi.nlm.nih.gov/pubmed/27038755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.03.047 |
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