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STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function
Mammalian CST (CTC1-STN1-TEN1) participates in multiple aspects of telomere replication and genome-wide recovery from replication stress. CST resembles Replication Protein A (RPA) in that it binds ssDNA and STN1 and TEN1 are structurally similar to RPA2 and RPA3. Conservation between CTC1 and RPA1 i...
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045167/ https://ncbi.nlm.nih.gov/pubmed/27690379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006342 |
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