Nonreplicating vaccinia vector efficiently expresses recombinant genes.
Modified vaccinia Ankara (MVA), a highly attenuated vaccinia virus strain that has been safety tested in humans, was evaluated for use as an expression vector. MVA has multiple genomic deletions and is severely host cell restricted: it grows well in avian cells but is unable to multiply in human and...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1992
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10847 |
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