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Palladium-Catalyzed Cross Coupling of Secondary and Tertiary Alkyl Bromides with a Nitrogen Nucleophile

[Image: see text] We report a new class of catalytic reaction: the thermal substitution of a secondary and or tertiary alkyl halide with a nitrogen nucleophile. The alkylation of a nitrogen nucleophile with an alkyl halide is a classical method for the construction of C–N bonds, but traditional subs...

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Publicado en:ACS Cent Sci
Autores principales: Peacock, D. Matthew, Roos, Casey B., Hartwig, John F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2016
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043439/
https://ncbi.nlm.nih.gov/pubmed/27725963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00187
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