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Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment

Cells are known to respond to physical cues from their microenvironment such as matrix rigidity. Discrete adhesive ligands within flexible strands of fibronectin connect cell surface integrins to the broader extracellular matrix and are thought to mediate mechanosensing through the cytoskeleton-inte...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Attwood, Simon J., Cortes, Ernesto, Haining, Alexander William M., Robinson, Benjamin, Li, Danyang, Gautrot, Julien, del Río Hernández, Armando
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043376/
https://ncbi.nlm.nih.gov/pubmed/27686622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34334
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