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Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment

Cells are known to respond to physical cues from their microenvironment such as matrix rigidity. Discrete adhesive ligands within flexible strands of fibronectin connect cell surface integrins to the broader extracellular matrix and are thought to mediate mechanosensing through the cytoskeleton-inte...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Attwood, Simon J., Cortes, Ernesto, Haining, Alexander William M., Robinson, Benjamin, Li, Danyang, Gautrot, Julien, del Río Hernández, Armando
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043376/
https://ncbi.nlm.nih.gov/pubmed/27686622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34334
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