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The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells

The angiogenic inducer CCN1 (Cysteine-rich 61, CYR61) is differentially activated in metastatic breast carcinomas. However, little is known about the precise mechanisms that underlie the pro-metastatic actions of CCN1. Here, we investigated the impact of CCN1 expression on fatty acid synthase (FASN)...

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Опубликовано в: :Oncoscience
Главные авторы: Menendez, Javier A., Vellon, Luciano, Espinoza, Ingrid, Lupu, Ruth
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043073/
https://ncbi.nlm.nih.gov/pubmed/27713913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.314
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