SIRT7, H3K18ac, and ELK4 Immunohistochemical Expression in Hepatocellular Carcinoma

BACKGROUND: SIRT7 is one of the histone deacetylases and is NAD-dependent. It forms a complex with ETS-like transcription factor 4 (ELK4), which deacetylates H3K18ac and works as a transcriptional suppressor. Overexpression of SIRT7 and deacetylation of H3K18ac have been shown to be associated with...

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Detalhes bibliográficos
Publicado no:J Pathol Transl Med
Main Authors: Lee, Hye Seung, Jung, Wonkyung, Lee, Eunjung, Chang, Hyeyoon, Choi, Jin Hyuk, Kim, Han Gyeom, Kim, Aeree, Kim, Baek-hui
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Pathologists and the Korean Society for Cytopathology 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042897/
https://ncbi.nlm.nih.gov/pubmed/27498548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2016.05.20
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