iPSC-derived cardiomyocytes reveal abnormal TGFβ signaling in left ventricular non-compaction cardiomyopathy

Left ventricular non-compaction (LVNC) is the third most prevalent cardiomyopathy in children and its pathogenesis has been associated with the developmental defect of the embryonic myocardium. We show that patient-specific induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) generated fr...

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Pubblicato in:Nat Cell Biol
Autori principali: Kodo, Kazuki, Ong, Sang-Ging, Jahanbani, Fereshteh, Termglinchan, Vittavat, Hirono, Keiichi, InanlooRahatloo, Kolsoum, Ebert, Antje D., Shukla, Praveen, Abilez, Oscar J., Churko, Jared M., Karakikes, Ioannis, Jung, Gwanghyun, Ichida, Fukiko, Wu, Sean M., Snyder, Michael P., Bernstein, Daniel, Wu, Joseph C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042877/
https://ncbi.nlm.nih.gov/pubmed/27642787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3411
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