Lineage-specific and single cell chromatin accessibility charts human hematopoiesis and leukemia evolution

We define the chromatin accessibility and transcriptional landscapes in thirteen human primary blood cell types that traverse the hematopoietic hierarchy. Exploiting the finding that the enhancer landscape better reflects cell identity than mRNA levels, we enable “enhancer cytometry” for enumeration...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Genet
Main Authors: Corces, M. Ryan, Buenrostro, Jason D., Wu, Beijing, Greenside, Peyton G., Chan, Steven M., Koenig, Julie L., Snyder, Michael P., Pritchard, Jonathan K., Kundaje, Anshul, Greenleaf, William J., Majeti, Ravindra, Chang, Howard Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042844/
https://ncbi.nlm.nih.gov/pubmed/27526324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3646
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker