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The monoclonal CD4 antibody M-T413 inhibits cellular infection with human immunodeficiency virus after viral attachment to the cell membrane: an approach to postexposure prophylaxis.

Infectious cellular uptake of human immunodeficiency virus (HIV) is initiated by a complex sequence of interactions between the viral envelope gp120/gp41 complex and the cellular CD4 receptor resulting in the exposure of a hydrophobic region of gp41 that mediates the irreversible fusion of the virus...

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Bibliografske podrobnosti
Main Authors: Rieber, E P, Federle, C, Reiter, C, Krauss, S, Gürtler, L, Eberle, J, Deinhardt, F, Riethmüller, G
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC50428/
https://ncbi.nlm.nih.gov/pubmed/1438278
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