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Apoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment

Zoledronate is one of the most potent nitrogen-containing bisphosphonates which has been demonstrated to result in osteoblast apoptosis and impact osteogenic differentiation in vitro. This effect of Zoledronate on osteoblasts may partially explain bisphosphonate-associated osteonecrosis of the jaw,...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Hu, Longwei, Han, Jing, Yang, Xi, Wang, Yang, Pan, Hongya, Xu, Liqun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042767/
https://ncbi.nlm.nih.gov/pubmed/27573706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5669
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