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Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis

Retinoic acid receptor β (RARβ), a known tumor suppressor gene, is frequently silenced in numerous malignant types of tumor. Recent reports have demonstrated that loss of RARβ expression may be responsible, in part, for the drug resistance observed in clinical trials. However, little is known about...

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Publicado en:Mol Med Rep
Main Authors: Ren, Hong-Yue, Chen, Bo, Huang, Gui-Li, Liu, Yu, Shen, Dong-Yan
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042735/
https://ncbi.nlm.nih.gov/pubmed/27599527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5701
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