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Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis

Retinoic acid receptor β (RARβ), a known tumor suppressor gene, is frequently silenced in numerous malignant types of tumor. Recent reports have demonstrated that loss of RARβ expression may be responsible, in part, for the drug resistance observed in clinical trials. However, little is known about...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Ren, Hong-Yue, Chen, Bo, Huang, Gui-Li, Liu, Yu, Shen, Dong-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042735/
https://ncbi.nlm.nih.gov/pubmed/27599527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5701
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