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Inhibition of Wnt/β‐catenin signaling downregulates P‐glycoprotein and reverses multi‐drug resistance of cholangiocarcinoma

The development of multi‐drug resistance (MDR) represents a major obstacle in the successful treatment of cancers. However, the factors and mechanisms that lead to MDR in cholangiocarcinoma (CCA), a chemoresistant bile duct carcinoma with a poor prognosis, remain unclear. In this study, we establish...

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Publicat a:Cancer Sci
Autors principals: Shen, Dong‐Yan, Zhang, Wei, Zeng, Xin, Liu, Chang‐Qin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656555/
https://ncbi.nlm.nih.gov/pubmed/23822562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12223
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