Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

Memories are assumed to be formed by sets of synapses changing their structural or functional performance. The efficacy of forming new memories declines with advancing age, but the synaptic changes underlying age-induced memory impairment remain poorly understood. Recently, we found spermidine feedi...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Gupta, Varun K., Pech, Ulrike, Bhukel, Anuradha, Fulterer, Andreas, Ender, Anatoli, Mauermann, Stephan F., Andlauer, Till F. M., Antwi-Adjei, Emmanuel, Beuschel, Christine, Thriene, Kerstin, Maglione, Marta, Quentin, Christine, Bushow, René, Schwärzel, Martin, Mielke, Thorsten, Madeo, Frank, Dengjel, Joern, Fiala, André, Sigrist, Stephan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042543/
https://ncbi.nlm.nih.gov/pubmed/27684064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002563
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