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E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell Proliferation

RNF12/RLIM is a RING domain-containing E3 ubiquitin ligase whose function has only begun to be elucidated recently. Although RLIM was reported to play important roles in some biological processes such as imprinted X-chromosome inactivation and regulation of TGF-β pathway etc., other functions of RLI...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gao, Rui, Wang, Lan, Cai, Hao, Zhu, Jingjing, Yu, Long
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042457/
https://ncbi.nlm.nih.gov/pubmed/27684546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164086
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