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Parkinson-associated risk variant in enhancer element produces subtle effect on target gene expression
Genome-wide association studies (GWAS) have identified numerous genetic variants associated with complex diseases but mechanistic insights are impeded by the lack of understanding of how specific risk variants functionally contribute to the underlying pathogenesis(1). It has been proposed that cis-a...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042324/ https://ncbi.nlm.nih.gov/pubmed/27096366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17939 |
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