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Effects of substrate conformational strain on binding kinetics of catalytic antibodies
We analyzed the correlation between the conformational strain and the binding kinetics in antigen-antibody interactions. The catalytic antibodies 6D9, 9C10, and 7C8 catalyze the hydrolysis of a nonbioactive chloramphenicol monoester derivative to generate a bioactive chloramphenicol. The crystal str...
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| Publicado no: | Biophys Physicobiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society of Japan (BSJ)
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042168/ https://ncbi.nlm.nih.gov/pubmed/27924267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.13.0_135 |
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