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Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains
Son of sevenless (SOS) is a guanine nucleotide exchange factor that regulates cell behavior by activating the small GTPase RAS. Recent in vitro studies have suggested that an interaction between SOS and the GTP-bound active form of RAS generates a positive feedback loop that propagates RAS activatio...
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| Publicado en: | Biophys Physicobiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society of Japan (BSJ)
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042160/ https://ncbi.nlm.nih.gov/pubmed/27924253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.13.0_1 |
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