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Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor.

We have isolated a cDNA from a mouse brain library that encodes a protein whose predicted amino acid sequence is 42% identical and 64% similar to that of the amyloid beta protein precursor (APP). This 653-amino acid protein, which we have termed the amyloid precursor-like protein (APLP), appears to...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wasco, W, Bupp, K, Magendantz, M, Gusella, J F, Tanzi, R E, Solomon, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1279693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10758
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