Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17.

Mouse trisomy 16 has been proposed as an animal model of Down syndrome (DS), since this chromosome contains homologues of several loci from the q22 band of human chromosome 21. The recent mapping of the defect causing familial Alzheimer disease (FAD) and the locus encoding the Alzheimer amyloid beta...

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Hauptverfasser: Cheng, S V, Nadeau, J H, Tanzi, R E, Watkins, P C, Jagadesh, J, Taylor, B A, Haines, J L, Sacchi, N, Gusella, J F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC281899/
https://ncbi.nlm.nih.gov/pubmed/2901095
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