Tumor suppressor PRSS8 targets Sphk1/S1P/Stat3/Akt signaling in colorectal cancer

PRSS8 is a membrane-anchored serine protease prostasin and has been shown an association with carcinogenesis. Herein we found that PRSS8 expression was significantly reduced in colorectal adenomas and adenocarcinomas. The decreased PRSS8 was well correlated with clinical stages, poor differentiation...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bao, Yonghua, Li, Kai, Guo, Yongchen, Wang, Qian, Li, Zexin, Yang, Yiqiong, Chen, Zhiguo, Wang, Jianguo, Zhao, Weixing, Zhang, Huijuan, Chen, Jiwang, Dong, Huali, Shen, Kui, Diamond, Alan M., Yang, Wancai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042014/
https://ncbi.nlm.nih.gov/pubmed/27050145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8511
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