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Slug inhibits the proliferation and tumor formation of human cervical cancer cells by up-regulating the p21/p27 proteins and down-regulating the activity of the Wnt/β-catenin signaling pathway via the trans-suppression Akt1/p-Akt1 expression

Slug (Snai2) has been demonstrated to act as an oncogene or tumor suppressor in different human cancers, but the function of Slug in cervical cancer remains poorly understood. In this study, we demonstrated that Slug could suppress the proliferation of cervical cancer cells in vitro and tumor format...

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Pubblicato in:Oncotarget
Autori principali: Cui, Nan, Yang, Wen-Ting, Zheng, Peng-Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041971/
https://ncbi.nlm.nih.gov/pubmed/27036045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8434
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