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Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis

Hepatic metastasis is the major cause of mortality in colorectal cancer (CRC) patients. Using proteomic analysis, we found sciellin (SCEL) to be specifically expressed in hepatic metastatic CRC cell lines. SCEL knockdown increased CRC cell migration and invasion, while overexpression had the opposit...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chou, Chuan-Kai, Fan, Chi-Chen, Lin, Pei-Shan, Liao, Pei-Yu, Tung, Jia-Chen, Hsieh, Chang-Hsun, Hung, Mien-Chie, Chen, Chung-Hsuan, Chang, Wei-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041940/
https://ncbi.nlm.nih.gov/pubmed/27013588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8264
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