Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis

BACKGROUND: The epithelial-to-mesenchymal transition (EMT) process results in a loss of cell-cell adhesion, increased cell mobility, and is crucial for enabling the metastasis of cancer cells. Recently, the enzyme SIRT1 has been implicated in a variety of physiological processes; however, its role i...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Chen, I-Chieh, Chiang, Wei-Fan, Huang, Hsin-Hsiu, Chen, Pei-Fen, Shen, Ying-Ying, Chiang, Hung-Che
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258025/
https://ncbi.nlm.nih.gov/pubmed/25424420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-254
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