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Role of SIRT3 in the regulation of redox balance during oral carcinogenesis
BACKGROUND: Sirtuins (SIRT1-7) are a family of NAD-dependent deacetylases, which play an important role in regulating cancer tumorigenesis; however, their role in oral cancer has been controversial. SIRT3 is localized in the mitochondria, where it deacetylates and activates several enzymes involved...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694519/ https://ncbi.nlm.nih.gov/pubmed/23800187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-68 |
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