Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma

Salivary adenoid cystic carcinoma (SACC) is characterized by invasive local growth and a high incidence of lung metastasis. Patients with lung metastasis have a poor prognosis. Treatment of metastatic SACC has been unsuccessful, largely due to a lack of specific targets for the metastatic cells. In...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Liu, Shuli, Ye, Dongxia, Xu, Dongliang, Liao, Yueling, Zhang, Ling, Liu, Liu, Yu, Wenwen, Wang, Yanan, He, Yue, Hu, Jingzhou, Guo, Wenzheng, Wang, Tong, Sun, Beibei, Song, Hongyong, Yin, Huijing, Liu, Jingyi, Wu, Yadi, Zhu, Hanguang, Zhou, Binhua P., Deng, Jiong, Zhang, Zhiyuan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041901/
https://ncbi.nlm.nih.gov/pubmed/26958807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7940
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