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Down-regulating cyclin-dependent kinase 9 of alloreactive CD4(+) T cells prolongs allograft survival

CDK9 (Cyclin-dependent kinase 9)/Cyclin T1/RNA polymerase II pathway has been demonstrated to promote the development of several inflammatory diseases, such as arthritis or atherosclerosis, however, its roles in allotransplantation rejection have not been addressed. Here, we found that CDK9/Cyclin T...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhan, Yang, Han, Yeming, Sun, Hukui, Liang, Ting, Zhang, Chao, Song, Jing, Hou, Guihua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041884/
https://ncbi.nlm.nih.gov/pubmed/27102157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8804
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