Immunomodulatory effects of nicotine on interleukin 1β activated human astrocytes and the role of cyclooxygenase 2 in the underlying mechanism

BACKGROUND: The cholinergic anti-inflammatory pathway (CAP) primarily functions through acetylcholine (ACh)-alpha7 nicotinic acetylcholine receptor (α7nAChR) interaction on macrophages to control peripheral inflammation. Interestingly, ACh can also bind α7nAChRs on microglia resulting in neuroprotec...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Revathikumar, Priya, Bergqvist, Filip, Gopalakrishnan, Srividya, Korotkova, Marina, Jakobsson, Per-Johan, Lampa, Jon, Le Maître, Erwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041575/
https://ncbi.nlm.nih.gov/pubmed/27681882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0725-1
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi