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Cytosolic NADH-NAD(+) Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging

Aim: Cytosolic NADH-NAD(+) redox state is central to cellular metabolism and a valuable indicator of glucose and lactate metabolism in living cells. Here we sought to quantitatively determine NADH-NAD(+) redox in live cells and brain tissue using a fluorescence lifetime imaging of the genetically-en...

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Bibliografske podrobnosti
izdano v:Antioxid Redox Signal
Main Authors: Mongeon, Rebecca, Venkatachalam, Veena, Yellen, Gary
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041510/
https://ncbi.nlm.nih.gov/pubmed/26857245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6593
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